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Authors
Monica Del-Rio-Vellosillo; Elena Rubio-Velazquez; Raquel Agustina Góngora-Rodríguez; Dolores Párraga-Muñoz; Vicente Zanon-Moreno; Maria D. Pinazo-Duran; Juan Jose Zafra-Perez; Jose Javier Garcia Medina

Retinal thickness and vascular parameters estimated by OCT and OCT angiography in autism spectrum disorder

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Abstract/Introduction

Purpose : The aim of this study was to compare retinal thicknesses and vascular parameters between autism spectrum disorder (ASD) and neurotypical (NT) individuals.

Methods : 14 eyes of 14 high-functioning ASD subjects and 14 eyes of 14 age- and sex-matched NT participants underwent 4 scans with the device Cirrus HD-OCT 5000 (Zeiss): macular cube, optic nerve cube, macular and optic nerve head (ONH) OCT angiography (OCT-A). Concerning OCT, thickness of full retina in 9 sectors of macular ETDRS pattern and peripapillary retinal nerve fiber layer (pRNFL) in 4 quadrants and 12 clock-hour sectors were considered. Vessel density and capillary perfusion density in 9 sectors were measured using macular OCT-A. ONH OCT-A estimated perfusion density and flux index in 4 peripapillary quadrants. Comparions between groups of these parameters were performed using U Mann-Whitney test.


Conclusion/Results

Results : ASD subjects showed higher ONH perfusion density and lower ONH flux index at the inferior quadrant when compared with NT individuals (p<0.05). Plus, a trend towards higher macular thickness, higher pRNFL thickness at inferior clock-hour sectors and higher macular vessel density and perfusion was observed in ASD.

Conclusions : Retinas of ASD subjects may present some structural and vascular differences when compared with retinas of NT individuals.


Testimonials


I haven't actually used the optometrist side, so my review is limited to the vision therapy offered.  This office was recommended by my occupational therapist for the treatment of my double vision following a stroke.


Claire A.

Love this location. I had a brain injury accident from day one one. All the team make you feel you still important and hope in the horizon after when the medical system fell you miserably. Dr. Ikeda very professional and very understanding about your issue. Two tombs up.


Jim K.

My husband and I were immediately impressed with Dr Ikeda. I was hit by a car while cycling which caused broken bones and three brain injuries. The brain injuries caused double vision. Dr. Ikeda examined my eyes and got me started on vision therapy with his occupational therapist who specializes in vision therapy.  She (Chris) is absolutely great.  I am impressed with the array of tools used to help recover my binocular vision.  I am doing things I never thought were possible (balance boards etc).  Chris pushes me and keeps me motivated. I really enjoy my sessions with her.  The office staff is always friendly and they have a wonderful appointment reminder tool that makes it easy to keep my calendar up to date. I am happy the rehab center at Little Co. of Mary recommended them!!


Teresa S.

The Vision Therapy is handled in a separate office through a different door from the shared waiting room. Chris, the vision therapist, has a wide and varied assortment of tools, equipment and resources to best evaluate and treat most vision issues. After just a few visits, my double vision became easier to control, using exercises developed during the therapy process. It was time well-spent.


Joe M.

I have been coming here since I can remember. I love it here. The staff is so amazing and nice. They explain everything they gonna do and never make you feel rushed. Dr. Ikeda has always been my doctor and I would never want another one. He is the doctor for my whole family and is always asking how everyone is doing. I am also so crazy about picking out my frames and have to try so many and each person who helps me take the time and lets me try them all on. I would never want to go anywhere else! I definitely would recommend this office to anyone looking for a great eye doctor.


Kayla W.

This is not for the eye exam but for the frames selection portion. I brought my prescription from Kaiser here with my VSP insurance. The reception staff was very polite and professional.  Manny helped me to pick out frames and explain my coverage.  Very helpful and patient not like the individual at the other place I rated here on Yelp.  I was running late and he still helped me and was not bothered at all.  I am so glad I came here ..........very pleased.

Very professional staff and pleasant.


Daniel G.
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